Pengaruh Continuous Improvement terhadap Kinerja Keberlanjutan dengan Sistem Digital Sebagai Variabel Mediasi: Studi Empiris pada Perusahaan di Industri Farmasi
Downloads
Industri farmasi menghadapi tekanan yang semakin besar untuk meningkatkan kinerja keberlanjutan (sustainability performance) yang mencakup dimensi ekonomi, lingkungan, dan sosial. Continuous improvement (CI) dan sistem digital dipandang sebagai faktor kunci dalam mendukung pencapaian kinerja keberlanjutan, namun penelitian yang mengkaji peran mediasi sistem digital dalam hubungan keduanya masih terbatas. Penelitian ini bertujuan untuk menganalisis pengaruh continuous improvement terhadap kinerja keberlanjutan (ekonomi, lingkungan, dan sosial) dengan sistem digital sebagai variabel mediasi pada perusahaan manufaktur farmasi. Dengan menggunakan pendekatan survei kuantitatif, data dikumpulkan dari 202 responden di berbagai bidang fungsional dan tingkat pekerjaan dalam sektor manufaktur farmasi. Kami menganalisis data menggunakan Structural Equation Modeling (SEM) dengan software AMOS untuk menguji hubungan langsung dan tidak langsung antar variabel. Hasilnya menunjukkan bahwa perbaikan berkelanjutan berdampak positif pada sistem digital. Selain itu, perbaikan berkelanjutan secara signifikan meningkatkan kinerja keberlanjutan ekonomi, lingkungan, dan sosial. Temuan ini juga menunjukkan bahwa sistem digital secara signifikan memediasi hubungan antara perbaikan berkelanjutan dan seluruh aspek kinerja keberlanjutan. Hal ini menunjukkan bahwa menggabungkan praktik perbaikan berkelanjutan dengan penerapan sistem digital akan meningkatkan pencapaian kinerja berkelanjutan. Studi ini menambah literatur yang ada dengan memberikan bukti bagaimana perbaikan berkelanjutan dan sistem digital bekerja sama untuk mendukung keberlanjutan dalam manufaktur farmasi. Secara praktis, temuan ini menekankan perlunya menghubungkan inisiatif perbaikan berkelanjutan dengan strategi transformasi digital untuk meningkatkan daya saing dan keberlanjutan jangka panjang.
Abobakr, M. A., Abdel-Kader, M. G., & Elbayoumi, A. F. (2022). The impact of lean manufacturing practices on sustainability performance: A natural resource-based view. Journal of Modern Accounting and Auditing, 18(3), 115–130.
Ali, H., Chen, T., & Hao, Y. (2021). Sustainable manufacturing practices, competitive capabilities, and sustainable performance: Moderating role of environmental regulations. Sustainability, 13(18), 10051. https://doi.org/10.3390/su131810051
Antunes, M. G., Quirós, J. T., & Justino, M. R. F. (2021). Effects of total quality management (TQM) dimensions on innovation: Evidence from SMEs. Sustainability, 13(18), 10095. https://doi.org/10.3390/su131810095
Azzahra, D. L., & Santosa, W. (2024). The influence of Internet of Things and supply chain collaboration on sustainable performance. COSTING: Journal of Economic, Business and Accounting, 7(5), 3761–3783. https://doi.org/10.31539/costing.v7i5.11021
Bade, C., Olsacher, A., Boehme, P., Truebel, H., Burger, L., Fehring, L. (2024). Sustainability in the pharmaceutical industry. Corporate Social Responsibility and Environmental Management, 31(1), 224–242. https://doi.org/10.1002/csr.2564
Bernal-Torres, C. A., Agudelo-Otálora, L. M., Paipa-Galeano, L., Jarrah-Nezhad, Y., & Millán, J. (2021). Continuous improvement and business sustainability in companies of an emerging market: Empirical analysis. Sustainability, 13(8), 4264. https://doi.org/10.3926/jiem.3610
Chen, Q., Ping, L., Dong, R., Li, C & Mao, S. (2025). The impact of artificial intelligence on sustainable development performance of medical/public supply chains. Technological Forecasting and Social Change, 190, 122417. https://doi.org/10.3389/fpubh.2025.1549283
Costa, F., Garza-Reyes, J. A., Kumar, V., & Antony, J. (2024). Integrating Industry 4.0 and lean manufacturing for a sustainable production model. Production Planning & Control, 35(3), 227–243. https://doi.org/10.1016/j.jclepro.2024.142728
Deng, D., Zhang, Y., Li, H., & Wang, J. (2024). Sustainable balanced scorecard and hybrid MCDM approach for pharmaceutical companies. Frontiers in Public Health, 12, 1298476. https://doi.org/10.3389/fpubh.2024.1495156
Fang, Q., Despeisse, M., & Johansson, B. (2025). Review of resource efficiency assessments in manufacturing: An integration model for production information systems. Journal of Cleaner Production, 418, 139890. https://doi.org/10.1016/j.cesys.2025.100318
Fitzgerald, J. (2025). Emerging digital innovations in pharmaceutical manufacturing quality: A systematised review. Journal of Pharmaceutical Innovation, 20(2), 145–162. https://doi.org/10.1007/s12247-025-10272-5
Khan, H. U., Ali, S., & Hongqi, L. (2018). Impact of continuous improvement on organization performance: Insight from Pakistan. International Journal of Innovation, Management and Technology, 9(1), 7–13. https://doi.org/10.18178/ijimt.2018.9.1.779
Kosasih, W., Pujawan, I. N., Karningsih, P. D., & Shee, H. (2023). Integrated lean-green practices and supply chain sustainability framework. Cleaner and Responsible Consumption, 11, 100143. https://doi.org/10.1016/j.clrc.2023.100143
Li, H., & Thurasamy, R. (2025). Green supply chain integration and sustainable performance in pharmaceutical industry of China: A moderated mediation model. Systems, 13(5), 388. https://doi.org/10.3390/systems13050388
Lizarelli, F. L., Antony, J., Suarez, M., Carneiro, F., Sony, M., Chakraborty, A., Ma, J., Chan, F (2025). Analysis of the impact of Kaizen practices on ESG performance and the mediating role of digital systems. Business Process Management Journal. https://doi.org/10.1108/BPMJ-01-2025-0056
Lyama, L. A., & Salema, G. L. (2025). Effect of lean manufacturing practices on manufacturing firms’ sustainability performance. International Journal of Industrial Engineering and Operations Management. https://doi.org/10.1108/IJIEOM-02-2025-0019
Ma, J.-Y., Shi, L., & Kang, T.-W. (2023). The effect of digital transformation on the pharmaceutical sustainable supply chain performance: The mediating role of information sharing and traceability using structural equation modeling. Sustainability, 15(1), 649. https://doi.org/10.3390/su15010649
Malesios, C., De, D., Moursellas, A., Dey, P. K., & Evangelinos, K. (2020). Sustainability performance analysis of small and medium-sized enterprises: Criteria, methods and framework. Journal of Cleaner Production, 256, 120475. https://doi.org/10.1016/j.seps.2020.100993
Mastrantonas, A., Doukas, H., & Psarras, J. (2024). Identifying the effects of Industry 4.0 in the pharmaceutical sector. Environmental Science and Pollution Research, 31, 22874–22890. https://doi.org/10.1007/s43621-024-00716-2
Maware, C., Okwu, M. O., & Adetunji, O. (2021). A systematic literature review of lean manufacturing implementation in manufacturing-based sectors of developing and developed countries. Journal of Industrial Engineering and Management, 14(2), 242–266. https://doi.org/10.1108/IJLSS-12-2020-0223
Mohaghegh, M., Blasi, S., & Russo, I. (2024). Digital transformation and sustainable performance: The mediating role of triple-A supply chain capabilities. Technological Forecasting and Social Change, 188, 122259. https://doi.org/10.1108/JBIM-02-2023-0098
Nigatu, A. (2022). The effect of Kaizen implementation and sustainability on the performance of the manufacturing sector in Ethiopia. Texila International Journal of Management, 8(2), Article 001. https://doi.org/10.21522/TIJMG.2015.08.02.Art001
Shashi, M. (2023). Sustainable digitalization in pharmaceutical supply chains using theory of constraints: A qualitative study. Sustainability, 15(11), 8752. https://doi.org/10.3390/su15118752
Sang, T.M., & Anh, N.Q. (2025). Adopting digital technology for sustainable performance: Circular economy practice in the transportation sector. Discover Sustainability, 6, Article 73. https://doi.org/10.1007/s43621-025-00973-9
Zuldekra. (2025). Prioritizing sustainable marketing innovation for pharmaceutical firms in Indonesia. Sustainability, 17(21), 9917. https://doi.org/10.3390/su17219917
Copyright (c) 2026 Ditosando Yudonegoro, Wahyuningsih Santosa , Tri Wulandari Satitidjati Dewayana , Yanu Agung Priyanto

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International (CC-BY-SA). that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.





