Establishing a TAVR Program in a Non-ECMO Center: Anesthetic Considerations and Safety Workflow
DOI:
https://doi.org/10.58344/locus.v5i7.6130Keywords:
transcatheter aortic valve replacement, general anesthesia, cardiac cardiac catheterization laboratory, rapid ventricular pacing, hemodynamic managementAbstract
Optimal anesthetic management during the initiation of a transcatheter aortic valve replacement (TAVR) program in centers without extracorporeal membrane oxygenation (ECMO) capability remains underexplored. This case report describes anesthetic considerations and contingency planning for establishing a new TAVR program in a cardiac catheterization laboratory. A 66-year-old male patient with severe aortic stenosis (valve area: 0.74 cm²; mean gradient: 43.89 mmHg; ejection fraction: 47%), coronary artery disease, congestive heart failure (NYHA class II), and chronic kidney disease stage III underwent transfemoral TAVR under general anesthesia as the inaugural procedure of the program. The procedure was performed in a cardiac catheterization laboratory without on-site ECMO support, with cardiac surgery standby and cardiopulmonary bypass equipment prepared in an adjacent operating room. Hemodynamic management during rapid ventricular pacing (180 beats/min for 10 seconds during balloon valvuloplasty and 120 beats/min during valve deployment) included preemptive phenylephrine boluses (total dose: 2 mg) and cautious crystalloid administration (500 mL). A 27 mm VitaFlow valve was successfully deployed. Post-deployment transesophageal echocardiography demonstrated mild paravalvular leak without intravalvular regurgitation or valve dislodgement. The patient was discharged on postoperative day 3 without complications. General anesthesia supported by structured hemodynamic management protocols and clearly defined cardiac surgery contingency planning enabled safe TAVR implementation during program initiation in a non-ECMO center. This case provides a practical framework for institutions establishing similar programs without immediate ECMO capability.
References
Abadié, G., et al. (2024). Feasibility and safety of transfemoral aortic valve replacement using local anesthesia in the catheterization suite versus general anesthesia in the operation theater. Catheterization and Cardiovascular Interventions. Advance online publication. https://doi.org/10.1002/ccd.70084
Aboali, A. A., et al. (2026). Safe and sound: Optimizing pediatric procedural sedation in emergency departments—From high-resource standards to low-resource adaptations: A state-of-the-art overview with practice recommendations and research agenda. Current Treatment Options in Pediatrics, 12(1), 11.
Angelillis, M., et al. (2022). Transcatheter aortic valve replacement with or without anesthesiologist: Results from a high-volume single center. Journal of Cardiovascular Medicine, 23(12), 785–791. https://doi.org/10.2459/JCM.0000000000001391
Augoustides, J. G. T., & Patel, P. A. (2018). Anesthetic options for transfemoral transcatheter aortic valve replacement—Is anesthetic evolution for the heart team inevitable? Journal of Cardiothoracic and Vascular Anesthesia, 32(3), 1341–1344. https://doi.org/10.1080/24748706.2018.1441572
Baxi, V. V., et al. (2024). Enhancing patient safety in critical care: Challenges, strategies, and emerging innovations. Journal of Medical and Dental Frontiers, 2(1), 16–24.
Billings, F. T., Kodali, S. K., & Shanewise, J. S. (2009). Transcatheter aortic valve implantation: Anesthetic considerations. Anesthesia & Analgesia, 109(5), 1453–1462. https://doi.org/10.1213/ANE.0B013E31819B07CE
Covello, R. D., Ruggeri, L., Landoni, G., Guarracino, F., & Bignami, E. (2010). Transcatheter implantation of an aortic valve: Anesthesiological management. Minerva Anestesiologica, 76(1), 32–40.
Dobson, G., et al. (2021). Guidelines to the practice of anesthesia—Revised edition 2021. Canadian Journal of Anesthesia, 68(1), 92–129.
Fassl, J., Kodavatiganti, R., & Ingerski, M. S. (2009). Anesthesia management for retrograde aortic valve replacement. Canadian Journal of Anesthesia, 56(3), 237–243. https://doi.org/10.1007/S12630-009-9064-3
Friess, J. O., Ariyakuddy, K. D., Eberle, B., & Erdoes, G. (2017). General anesthesia or monitored anesthesia care for transfemoral transcatheter aortic valve implantation: Current trends and future directions. Current Anesthesiology Reports, 7(3), 315–322. https://doi.org/10.1007/S40140-017-0225-6
Im, G. Y., et al. (2016). Early liver transplantation for severe alcoholic hepatitis in the United States—A single-center experience. American Journal of Transplantation, 16(3), 841–849.
Klein, A. A., et al. (2021). Recommendations for standards of monitoring during anaesthesia and recovery 2021: Guideline from the Association of Anaesthetists. Anaesthesia, 76(9), 1212–1223.
Ko, T. Y., Kao, H. L., Chen, Y. C., Yeh, C. C., & Huang, C. C. (2023). Results of streamlining TAVR procedure towards a minimalist approach: A single center experience in Taiwan. Scientific Reports, 13, Article 19945. https://doi.org/10.1038/s41598-023-46475-4
Larson, J. (2022). Education for nursing staff caring for extracorporeal life support patients.
Loberman, D., Shaefi, S., Mohr, J. P., Dombrowski, M., & Zelman, V. (2018). Trans-catheter aortic valve replacement program in a community hospital: Comparison with US national data. PLoS ONE, 13(10), e0204766. https://doi.org/10.1371/journal.pone.0204766
Moore, E. A., et al. (2026). ELSO 2025 narrative guideline on ECMO training and continuing education. ASAIO Journal, 72(4), 274.
Pani, S., Cagino, J., Feustel, P. J., Musuku, S. R., & Raja, A. (2017). Patient selection and outcomes of transfemoral transcatheter aortic valve replacement performed with monitored anesthesia care versus general anesthesia. Journal of Cardiothoracic and Vascular Anesthesia, 31(4), 1370–1375. https://doi.org/10.1053/j.jvca.2017.04.005
Pyne, S. G., et al. (2021). Patient selection criteria in ambulatory surgery—A single-center experience to reflect on development, implementation and evaluation of its impact. Ambulatory Surgery, 27, 64–68.
Ree, R. M., Bowering, J. B., & Schwarz, S. K. W. (2008). Case series: Anesthesia for retrograde percutaneous aortic valve replacement—Experience with the first 40 patients. Canadian Journal of Anesthesia, 55(11), 761–768. https://doi.org/10.1007/BF03016349
Ruggeri, L., Gerli, C., Franco, A., Barile, L., & Magnano di San Lio, M. S. (2012). Anesthetic management for percutaneous aortic valve implantation: An overview of worldwide experiences. HSR Proceedings in Intensive Care & Cardiovascular Anesthesia, 4(1), 40–46.
Sammour, Y., Kerrigan, J., Banerjee, K., Gajulapalli, R. D., & Lak, H. M. (2021). Comparing outcomes of general anesthesia and monitored anesthesia care during transcatheter aortic valve replacement: The Cleveland Clinic Foundation experience. Catheterization and Cardiovascular Interventions, 97(7), E1022–E1030. https://doi.org/10.1002/CCD.29496
Scott, M. J. (2023). Perioperative patients with hemodynamic instability: Consensus recommendations of the Anesthesia Patient Safety Foundation. Anesthesia & Analgesia, 138(4), 713–726.
Weitzel, N. S. (2015). Catheter-based cardiac surgery: Anesthesia in the hybrid suite and cath lab. ASA Refresher Courses in Anesthesiology, 43(1), 91–101. https://doi.org/10.1097/ASA.0000000000000032
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